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Several methods for infrared spectrometry of pharmaceutical plastic bottles

Aug 05 , 2019

Infrared spectrometry of pharmaceutical plastic bottles is an effective means to identify and analyze the chemical structure of substances. After being irradiated by infrared radiation, the compound causes the vibration and rotation of the molecule to transition from a lower energy level to a higher energy level, resulting in selective absorption of specific frequency infrared radiation, forming a characteristic infrared absorption spectrum. 


Several methods for infrared spectrometry of pharmaceutical plastic bottles

pharmaceutical packaging

Infrared spectroscopy method for pharmaceutical packaging: hot compress method, thin film method, attenuated total reflection method (ATR method). The first method of hot compressing, this method is applicable to the infrared spectrometric determination of pellets, plastic bottles and single-layer films. A potassium bromide wafer or a sodium chloride wafer was used to draw a spectrum by projection. The second method is a thin film method. The method is applicable to the infrared spectrometry of pellets, plastic bottles and single-layer films.


Several methods for infrared spectrometry of pharmaceutical plastic bottles

desiccant packaging

Take about 0.25g of sample (can be cut into small pieces), add suitable solvent (such as polyethylene bottle, polypropylene, ethylene and vinyl acetate copolymer can be used toluene: polyethylene terephthalate available tetrachloroethylene Alkane: Polycarbonate can be dichloroethane) about 10ml, the sample is dissolved at high temperature reflux, and the reflux liquid is coated on a potassium bromide wafer or a sodium chloride wafer by capillary heat. After heating and removing the solvent, the spectrum is drawn by transmission. . The third method Attenuation Total Reflection Method (ATR method) This method is applicable to the infrared spectrometric determination of pellets, pharmaceutical plastic bottles, films, hard sheets, and rubber products. The surface is cleaned and the sample is cleaned and pressed, and the wafer used to press the ATR accessory directly draws the spectrum by reflection.

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