Determination of abnormal toxicity of hdpe bottles for pharmaceutical

hdpe bottles for pharmaceutical abnormal toxicity test: take a few pharmaceutical packaging and wash with water, take 500cm2 (in terms of internal surface area), cut, add 50ml of sodium chloride injection, set high pressure steam sterilizer 110 degrees to maintain After 30 minutes, take it out, after cooling, as a test solution, use the same batch of sodium chloride injection as a blank, intravenous injection, and check according to law (Chinese Pharmacopoeia 2015 edition general rule 1141), should comply with the regulations.

hdpe bottles for pharmaceuticals

Abnormal toxicity refers to toxicity caused by introduction or other causes during the production process. This method is to give the animal a certain dose of the test solution, observe the abnormal reaction or death of the animal within the specified time, check whether the test article is contaminated with exogenous toxic substances and whether there are unexpected unsafe factors.

vitamin c tube

The test solution is prepared according to the concentration specified under the variety, and the forest is used for the test, and the test solution should be equilibrated to room temperature. It should be healthy and qualified. It should be kept under normal feeding conditions before the experiment and during the observation period of the test. Animals that have done this experiment should not be reused.