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Development trend of standardized determination of serum lipids in vitro diagnosis

Feb 19 , 2020

In order to meet the needs of prevention and treatment of cardiovascular diseases and clinical research, and make the determination of blood lipid in China in line with the international standards, in recent years, many domestic conferences on blood lipid have emphasized the importance of standardization of blood lipid determination. Dyslipidemia is an important risk factor for atherosclerotic cardiovascular diseases. Clinical and epidemiological studies on cardiovascular diseases, as well as the monitoring of blood lipid changes during the diagnosis or treatment of hyperlipidemia, all require an accurate and reliable inter-laboratory comparable measurement result. Therefore, the standardized measurement of blood lipid is very important.


Development trend of standardized determination of serum lipids in vitro diagnosis

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In recent years, the incidence and mortality of coronary heart disease in China have increased, which has aroused extensive attention from the health administration department and the medical community in China. However, the classification criteria, treatment guidelines and treatment targets of dyslipidemia in the medical community in China are still a chaotic situation. Up to now, the standardization of national lipids has not been carried out. "Dyslipidemia prevention countermeasures task force" was set up, for our country initially set the TC, TG, HDL, LDL - C - C and other four lipid appropriate range and increased levels of demarcation, this not only for screening of coronary heart disease risk individuals with specific criteria, and pointed out the diet and medication pointer, as well as the treatment required to achieve the target.

The standardization of blood lipid measurement is to achieve accurate measurement results, make the measurement values between laboratories comparable, and make the accuracy of routine measurement traceable to the recognized reference system. Only by achieving standardization, can the survey data of blood lipid levels between regions and between cities be comparable in the future. Lipid determination of standardization, it is a task arduous system engineering, establish leading institutions, to establish the reference system of our country, determine to recommend using standard methods and regulations, strengthening the management of production units, and the technical index of the kits and all calibration the matrix effect and the fixed value of content must be strictly in accordance with the requirements of the recommended method, regularly carry out room between qualitative evaluation, strengthening the consciousness of lipid measurement standardization and technical training, improve staff quality is the fundamental problem to be standardized, otherwise it will lead to the categorization of dangerous objects to make a mistake, or inappropriate treatment and treatment time delay. In addition, mutual understanding and cooperation between laboratories in different places can help standardize lipids.

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