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Desiccant packaging principle

Jul 02 , 2019

According to the effervescent tablet medicinal properties, the desiccant packaging principle is to place the desiccant in the cap and seal the bottle through the cap. The package has strict requirements on sealing properties, water molecule control, moisture resistance, water vapor transmission rate, and moisture content of the desiccant. The pharmaceutical packaging has achieved the purpose of absorbing water molecules by placing the desiccant in the cap, which requires the material to have good barrier properties to water molecules. Followed by the moisture content of the desiccant and the humidity of the production plant. All of these aspects will lead to the effectiveness of effervescent tablets.

Desiccant packaging principle    

desiccant packaging

The prescription for effervescent tablets consists of the main drug, diluent, binder, disintegrant, lubricant and other excipients. The diluents, binders, lubricants and other excipients used are the same as ordinary tablets. The appropriate variety needs to be selected according to the preparation process. Unlike ordinary tablets, the disintegrant used in effervescent tablets is an effervescent disintegrant, and the effervescent disintegrant includes an acid source and an alkali source. Commonly used acid sources are citric acid, malic acid, boric acid, tartaric acid, and rich. Horse acid, inorganic mineral acid (hydrochloric acid), etc.; commonly used alkali sources are sodium hydrogencarbonate, sodium carbonate and a mixture of the two. The ratio of acid to base has a significant effect on the preparation and stability of effervescent tablets. It is generally believed that the amount of acid exceeds the theoretical amount, which is beneficial to the stability of the effervescent tablet and the improvement of the mouthfeel.

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