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Quality requirements of cardboard of effervescent tube cap

May 20 , 2022

The effervescent tube is composed of tube body, bottle cap frame, desiccant, spring, cardboard, etc. It is a kind of medicine packaging with very good moisture-proof function. The quality of the pharmaceutical packaging is related to the stability and safety of the drug. In addition to the overall quality standard requirements for the packaging, the cardboard must also meet the quality requirements.


Quality requirements of cardboard of effervescent tube cap

144mm effervescent tube packaging


Cardboard is an important part of the bottle cap. It is attached to the top of the bottle cap and acts as a sealing part of the desiccant compartment to isolate the desiccant from direct contact with the drug. Cardboard is the part that is in direct contact with the effervescent tablet, and its composition, thickness, moisture content, etc. will affect the storage of drugs or the moisture-proof performance of packaging. For example, the function of cardboard is mainly to block and seal. Too much thickness will affect the performance of the desiccant, and too high moisture content will easily make the drug damp, stick, and deteriorate.


Quality requirements of cardboard of effervescent tube cap

92mm*21mm plastic tube for tablets


The quality requirements for effervescent tubes are the national standard of YBB00172004-2015 "Oral Solid Medicinal Low Density Polyethylene Moisture-Proof Combination Caps". The lead content should not exceed 0.0005%, and the drug contact surface should be inspected under ultraviolet lamps with wavelengths of 365mm and 254mm, and there should be no flake fluorescence. The thickness is recognized as 0.46-0.55mm pure high-quality wood pulp white cardboard in the industry.

The above are the quality requirements of effervescent tubes for cardboard. A high-quality effervescent tablet packaging not only has strict requirements on raw materials, components, and sealing, but also the moisture content of desiccant and short-term moisture absorption rate must meet the standard requirements, so as to ensure the drug Stability and safety during the validity period.


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