These factors affect the moisture-proof performance of medicine bottles

The moisture-proof performance of medicine bottles is crucial during the storage and use of drugs. Improper moisture-proof measures may cause the drug to become ineffective or deteriorate in quality, so it is necessary to understand and optimize its moisture-proof performance. The following are several major factors that affect the moisture-proof effect of medicine bottles.

desiccant bottle with silica gel

1. Selection and use of desiccant

Desiccant can effectively absorb moisture inside the package to prevent tablets or capsules from getting wet. However, the type, amount and placement of desiccant in the package directly affect its moisture-proof performance. For example, using a sufficient amount of silica gel desiccant usually provides a good moisture-proof effect, while inappropriate desiccant configuration may result in insufficient moisture-proof.

2. Selection of packaging materials

The moisture-proof performance of medicine bottles depends largely on the packaging materials used. Highly moisture-proof materials such as polyethylene and polypropylene can effectively block external moisture, thereby protecting the effervescent tablets inside. These materials usually have excellent moisture-proof capabilities and can effectively extend the shelf life of solid tablets. Therefore, choosing the right packaging material is a key step in improving moisture-proof performance.

3. Sealing of bottle cap and bottle mouth

The overall sealing of medicine bottles is crucial for moisture-proofing. The degree of fit between the bottle cap and the bottle mouth, whether the sealing is tight, and the dimensional accuracy of the bottle mouth will directly affect the moisture-proof effect. If the bottle cap is not sealed well or there are defects in the bottle mouth design, moisture may enter the package, thus affecting the quality of the effervescent tablets. Therefore, ensuring the perfect fit between the bottle cap and the bottle mouth is a necessary measure to maintain moisture-proof performance.

50ml desiccant bottle with CRC

4. Thickness and moisture content of cardboard

Cardboard also plays an important role in the packaging of oral solid pharmaceutical high-density polyethylene moisture-proof combination bottle caps, especially in terms of sealing and the use of desiccant. The thickness and moisture content of cardboard have a direct impact on the effect of desiccant. Too thick cardboard may hinder the effect of desiccant and reduce its moisture absorption capacity; while too high moisture content of cardboard may weaken the effect of desiccant because desiccant will preferentially absorb moisture from cardboard. Therefore, reasonable control of the thickness and moisture content of cardboard is another important factor to ensure the moisture-proof performance of medicine bottles.

In order to improve the moisture-proof performance of medicine bottles, it is necessary to start from multiple aspects. Selecting appropriate packaging materials, using desiccants correctly, ensuring the tightness of the bottle cap and bottle mouth, and reasonably controlling the thickness and moisture content of the paperboard, these factors work together to effectively improve the moisture-proof effect. By comprehensively optimizing these factors, the quality of solid preparations can be effectively protected and their stability during storage can be ensured.