The determination of the infrared spectrum of polyethylene bottles mainly refers to the effective means of identifying the substance and analyzing the chemical structure of pharmaceutical packaging by infrared spectroscopy. It can identify various information of polymer compounds and play an important role in determining the composition of materials. In order to control the formulation of pharmaceutical packaging materials by strengthening the control of materials, it is ensured that the use of drugs is safe and reliable. For the control of polymer materials, infrared spectroscopy is the most effective detection technology.
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The principle is that after the molecular compound of the pharmaceutical packaging container is irradiated by infrared radiation, the vibration and rotation of the molecule are enabled, and the lower energy can be switched to a higher energy level transition, thereby causing selective absorption of infrared radiation of a certain frequency to form a characteristic red. Light absorption spectrum.
Infrared spectrometry commonly used in polyethylene bottles can be divided into two categories:
One type refers to detection techniques: such as transmission method (British Pharmacopoeia, European Pharmacopoeia), multiple internal reflection method (MR), ATR American Pharmacopoeia method, immersion reflection method, photoacoustic spectroscopy, polarization infrared Method, specular reflection method, etc.
The other type refers to the sample preparation technology and the commonly used sample preparation techniques in the analysis of polymer compounds, such as direct method, solvent volatilization film formation method, solution method, slicing method, and thermal cracking method.
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